Recombinant Human CCL3 Protein

Recombinant Human CCL3 Protein

• Background: Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3.
• Abbreviation: CCL3
• Synonyms: C-C Motif Chemokine 3, CCL3, G0/G1 Switch Regulatory Protein 19-1, G0S19-1, MIP-1-Alpha, MIP1A, Macrophage Inflammatory Protein 1-Alpha, PAT 464.1, SCYA3, SIS-Beta, Small-Inducible Cytokine A3, Tonsillar Lymphocyte LD78 Alpha Protein
• CAS Number: 9000-83-3
• UniProt: P10147
• Accession Number: P10147
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Ala 27-Ala 92
• Applications: Cell culture
• Field of Research: immunology
• Purity: > 95 % as determined by reducing SDS-PAGE.
• Bioactivity: Measure by its ability to chemoattract human PBMC using a concentration range of 5 -50 ng/mL.
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 8-11 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.