Recombinant Human Survivin/BIRC5 Protein
CAT:
763-PKSH032109-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human Survivin/BIRC5 Protein
- Background: Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
- Abbreviation: Survivin;BIRC5
- Synonyms: API4, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, Baculoviral IAP Repeat-Containing Protein 5, IAP4
- CAS Number: 9000-83-3
- UniProt: O15392
- Accession Number: O15392
- Host: E. coli
- Origin Species: Human
- Tag: None
- Sequence: Met 1-Asp142
- Field of Research: Cell biology;Neuroscience;Cancer
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 16-18 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.