Recombinant Human AKR1C2 Protein

Recombinant Human AKR1C2 Protein

• Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
• Abbreviation: AKR1C2
• Synonyms: 2-Dihydrobenzene-1, 2-Diol Dehydrogenase, 3-Alpha-HSD3, Aldo-Keto Reductase Family 1 Member C2, Chlordecone Reductase Homolog HAKRD, DD-2, DD/BABP, DD2, Dihydrodiol Dehydrogenase 2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, Trans-1, Type III 3-Alpha-Hydro
• CAS Number: 9000-83-3
• UniProt: P52895
• Accession Number: P52895
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Met 1-Tyr323
• Field of Research: Signal Transduction;Cancer;metabolism;
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Not Applicable
• Molecular Weight: 35 kDa
• Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
• Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.