Recombinant Human METAP1 Protein (Fc Tag)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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Recombinant Human METAP1 Protein (Fc Tag)

CAT:

763-PKSH031734

Size:

50 µg

Price:

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For price, please contact [email protected].

Recombinant Human METAP1 Protein (Fc Tag)

Background: Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
Synonyms: MAP 1, MAP1A, METAP1, MetAP 1, MetAP1A, Methionine aminopeptidase 1, Peptidase M 1
UniProt: P53582
Accession Number: NP_055958.2
Host: HEK293 Cells
Origin Species: Human
Tag: N-hFc
Sequence: Met 1-Phe 272
Field of Research: Signal Transduction;metabolism;
Purity: > 85 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Please refer to the printed manual for detailed information.
Molecular Weight: 60-65 kDa
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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