Recombinant Human SIGLEC6/CD327 Protein (Fc Tag)

Recombinant Human SIGLEC6/CD327 Protein (Fc Tag)

• Background: SIGLEC6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC6 is a sialic acid recognizing protein expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. SIGLEC6 localizes in various compartments such as membrane fraction, extracellular region and so on. SIGLEC6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Interestingly, expression of SIGLEC6 is further upregulated in pre-eclampsia, which appears to be a uniquely human disease.
• Synonyms: CD327, CD33L, CD33L1, CD33L2, CDW327, OBBP1, SIGLEC6
• CAS Number: 9000-83-3
• UniProt: O43699
• Accession Number: O43699-3
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-hFc
• Sequence: Gln27-Val331
• Field of Research: Immunology
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 66-73 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.