Recombinant Human FABP5 Protein

Recombinant Human FABP5 Protein

• Background: Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.
• Synonyms: E-FABP, Epidermal-Type Fatty Acid-Binding Protein, FABP5, Fatty Acid-Binding Protein 5, Fatty Acid-Binding Protein Epidermal, PA-FABP, Psoriasis-Associated Fatty Acid-Binding Protein Homolog
• CAS Number: 9000-83-3
• UniProt: Q01469
• Accession Number: Q01469
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Met 1-Glu 135
• Field of Research: Signal Transduction;Cardiovascular;Cancer;metabolism;
• Purity: > 92 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.