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Recombinant Human FABP5 Protein

CAT: 0763-PKSH030810Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0763-PKSH030810Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fatty acid-binding protein; also known as Epidermal-type fatty acid-binding protein; Fatty acid-binding protein 5; Psoriasis-associated fatty acid-binding protein homolog; E-FABP and FABP5; is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins (FABPs) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids; as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.
Synonyms
E-FABP; Epidermal-Type Fatty Acid-Binding Protein; FABP5; Fatty Acid-Binding Protein 5; Fatty Acid-Binding Protein Epidermal; PA-FABP; Psoriasis-Associated Fatty Acid-Binding Protein Homolog
UniProt
Q01469
Accession Number
Q01469
Expression System
E.coli
Tag
None
Sequence
Met 1-Glu 135
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
Please contact us for more information.
Purity
> 92 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
15.2 kDa
Species
Human

UniProtKB · Q01469

Fatty acid-binding protein 5

FABP5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01469
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FABP5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R4K0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondPhosphoprotein

Cellular component

CytoplasmNucleusSecretedSynapse

Biological process

Lipid transportTransport

Ligand

Lipid-binding
Product Datasheet
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