Recombinant Human Mesothelin/MSLN Protein (Fc Tag)

Recombinant Human Mesothelin/MSLN Protein (Fc Tag)

• Background: Megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised by several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells; mesotheliomas; and ovarian cancer; but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas; ovarian cancers; and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.
• Synonyms: CAK1, CAK1 antigen, MPF, MSLN, Megakaryocyte potentiating factor, Pre-pro-megakaryocyte-potentiating factor, SMR, mesothelin, soluble MPF mesothelin related protein
• CAS Number: 9000-83-3
• UniProt: Q13421
• Accession Number: Q13421-2
• Host: HEK293 Cells
• Origin Species: Human
• Tag: C-hFc
• Sequence: Met 1-Arg286
• Field of Research: Tags & Cell Markers,Cancer
• Purity: > 99 % as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: Please refer to the printed manual for detailed information.
• Molecular Weight: 56 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.