Recombinant Human CD16b/FCGR3B Protein, Biotinylated

Recombinant Human CD16b/FCGR3B Protein, Biotinylated

• Background: Low affinity immunoglobulin gamma Fc region receptor III-B; also known as Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
• Synonyms: CD16b and FCGR6B, FCG3, FCGR3, FCRIII, FCRIIIb, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, Low affinity immunoglobulin gamma Fc region receptor III-B
• CAS Number: 9000-83-3
• UniProt: O75015
• Accession Number: O75015-1
• Host: E. coli
• Origin Species: Human
• Tag: None
• Sequence: Met 18-Gly 193
• Applications: ELISA
• Field of Research: Immunology
• Purity: > 90 % as determined by reducing SDS-PAGE.
• Bioactivity: 1. Measured by its ability to bind human IgG1 in a functional ELISA. 2. Labeling ratio of biotin to protein: 5. 51.
• Reconstitution: Please refer to the printed manual for detailed information.
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.