Cholesteryl linoleate-d11

Cholesteryl linoleate-d11

• UNSPSC Description: Cholesteryl linoleate-d11 is deuterium labeled Cholesteryl linoleate. Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions[1].
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Metabolic Disease
• Smiles: C[C@@]12C(C[C@H](CC1)OC(CCCCCCC/C=C\C/C=C\C([2H])(C([2H])(C([2H])(C([2H])([2H])C([2H])([2H])[2H])[2H])[2H])[2H])=O)=CC[C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@]4([H])[C@H](C)CCCC(C)C)[H])C)[H])[H]
• Molecular Weight: 660.15
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Huber J, et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):581-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported