Anti-MERS-CoV Nucleoprotein/NP Polyclonal Antibody

• Background:

  Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

• Host:

  Rabbit

• Reactivity:

  MERS-CoV

• Immunogen:

  Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag)

• Target:

  Coronavirus NP; coronavirus Nucleocapsid; coronavirus Nucleoprotein; cov np; ncov NP; novel coronavirus Nucleoprotein; NP; Nucleocapsid; Nucleoprotein

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  ELISA

• Purification:

  Protein A Affinity

• Concentration:

  1mg/mL

• Dilution:

  ELISA 1:1000-1:2000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG