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CD284 Polyclonal Antibody

CAT: 0763-E-AB-70375-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-70375-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Abbreviation
CD284
UniProt
O00206, Q9QUK6, Q9QX05
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse TLR4.
Target
ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Immunology; Microbiology
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
95kDa
Observed Molecular Weight
95kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0024320521008626
Citation 02
https://academic.oup.com/jpp/article-abstract/73/4/473/6118677
Isotype
IgG
Product Datasheet
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