CD284 Polyclonal Antibody

• Background:

  TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

• Abbreviation:

  CD284

• UniProt:

  O00206, Q9QUK6, Q9QX05

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse TLR4.

• Target:

  ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cardiovascular; Immunology; Microbiology

• Purification:

  Affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  95kDa

• Observed Molecular Weight:

  95kDa

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S0024320521008626

• Citation 02:

  https://academic.oup.com/jpp/article-abstract/73/4/473/6118677

• Isotype:

  IgG