MBP Polyclonal Antibody

• Background :

  MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

• Abbreviation :

  MBP

• UniProt :

  P04370, P02688

• Host :

  Rabbit

• Reactivity :

  Mouse; Rat

• Immunogen :

  KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein

• Target :

  GDB; Golli MBP; Golli MBP; myelin basic protein; Hemopoietic MBP; HMBPR; HUGO; MBP; MBP_CAVPO; MBP; MGC99675; MLD; Myelin A1 protein; Myelin A1 Protein; basic; Myelin basic protein; Myelin Deficient; Myelin membrane encephalitogenic protein; OTTHUMP00000163776; OTTHUMP00000174387; OTTHUMP00000174388; SHI; Shiverer; SP

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Neuroscience; Tags and Cell Markers

• Purification :

  Affinity purification

• Concentration :

  300 μg/mL

• Dilution :

  WB 1:500-1:1000; IHC 1:200-1:600

• Buffer :

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  17-22kDa

• Observed Molecular Weight :

  17-22kDa

• Isotype :

  IgG