CD156c Polyclonal Antibody

• Background:

  Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP) .

• Abbreviation:

  CD156c

• UniProt:

  O14672, O35598, Q10743

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse ADAM10

• Target:

  A disintegrin and metalloprotease domain 10; A disintegrin and metalloproteinase domain 10; AD 10; AD10; AD18; ADA10; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; CD 156c; CD156c; CD156c antigen; CDw156; disintegrin and metalloproteinase domain containing protein 10; Disintegrin and metalloproteinase domain-containing protein 10; HsT 18717; HsT18717; Kuz; Kuzbanian; Kuzbanian protein homolog; Kuzbanian; Drosophila; homolog of; MADM; Mammalian disintegrin metalloprotease; Mammalian disintegrin-metalloprotease; RAK

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cell Biology; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  210 μg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  84kDa

• Observed Molecular Weight:

  95kDa

• Isotype:

  IgG