CDC25A Polyclonal Antibody

• Background:

  CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  CDC25A

• UniProt:

  P30304, P48965, P48964

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A

• Target:

  Cdc 25a; CDC25A; CDC25A2; CDC25A2 CAG isoform; Cell division cycle 25 homolog A (S. pombe) ; Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform b; D9Ertd393e; Dual specificity phosphatase Cdc25A; M phase inducer phosphatase 1; M-phase inducer phosphatase 1; MGC115549; MPIP1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Epigenetics and Nuclear Signaling

• Purification:

  Affinity purification

• Concentration:

  0.96 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  65-70kDa

• Observed Molecular Weight:

  70kDa

• Isotype:

  IgG