TH Polyclonal Antibody

• Background:

  TH (Tyrosine 3-monooxygenase) converts L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA), the essential and rate-limiting step to formation of dopamine and other catecholamines. TH plays an important role in the physiology of adrenergic neurons and can be used as a marker for dopaminergic and noradrenergic neurons.

• Abbreviation:

  TH

• UniProt:

  P24529, P04177

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant protein corresponding to Mouse Tyrosine Hydroxylase

• Target:

  Dystonia 14; DYT14; DYT5b; EC 1.14.16.2; OTTHUMP00000011225; OTTHUMP00000011226; ple; Protein Pale; TH; The; TY3H; TYH; Tyrosine 3 hydroxylase; Tyrosine 3 monooxygenase; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; Tyrosine hydroxylase

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF

• Field of Research:

  Cancer; Metabolism; Neuroscience

• Purification:

  Affinity purification

• Concentration:

  370 μg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:300-1:800; IF 1:200-1:800

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  62kDa

• Observed Molecular Weight:

  62kDa

• Citation 01:

  https://link.springer.com/article/10.1007/s12640-023-00637-4

• Citation 02:

  https://link.springer.com/article/10.1007/s11064-022-03600-5

• Citation 03:

  https://link.springer.com/article/10.1007/s00213-020-05605-w

• Citation 04:

  https://www.sciencedirect.com/science/article/pii/S0006899322001822

• Citation 05:

  https://link.springer.com/article/10.1007/s11064-020-03186-w

• Citation 06:

  https://www.sciencedirect.com/science/article/pii/S0166432820303910

• Citation 07:

  https://www.sciencedirect.com/science/article/pii/S0304394020305784

• Citation 08:

  https://www.scielo.br/j/bjps/a/Kr44c8ynTSz6xNycgpC94md/abstract/?lang=en

• Isotype:

  IgG