PTEN Polyclonal Antibody

CAT: 0763-E-AB-70070-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0763-E-AB-70070-01Size:60 μL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.
Abbreviation
PTEN
UniProt
P60484, O08586
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PTEN
Target
10q23del; BZS; DEC; GLM2; MGC11227; MHAM; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; Phosphatase and tensin like protein; Phosphatidylinositol 3;4;5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Pten; PTEN; PTEN1; TEP1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
480 μg/mL
Dilution
IHC 1:100-1:500
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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