CD8A Polyclonal Antibody

• Background :

  The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation :

  CD8A

• UniProt :

  P01732

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Recombinant fusion protein of human CD8A

• Target :

  CD8A; CD8; Leu2; MAL; p32

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Immunology; Stem Cells

• Purification :

  Affinity purification

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:50-1:200

• Buffer :

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  21kDa/25kDa/30kDa

• Observed Molecular Weight :

  26KDa

• Isotype :

  IgG