TMPRSS2 Polyclonal Antibody

• Background:

  This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  TMPRSS2

• UniProt:

  O15393

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant fusion protein of human TMPRSS2 (NP_001128571.1) .

• Target:

  TMPRSS2; PP9284; PRSS10

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cell Biology; Neuroscience

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  53kDa/57kDa

• Observed Molecular Weight:

  52kDa

• Isotype:

  IgG