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MCAM Polyclonal Antibody

CAT: 0763-E-AB-53284-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-53284-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) .
Abbreviation
MCAM
UniProt
P43121
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human MCAM
Target
A32 antigen; CD 146; CD146; CD146 antigen; Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Gicerin; Mcam; Melanoma adhesion molecule; Melanoma associated antigen A32; Melanoma associated antigen MUC18; Melanoma associated glycoprotein MUC18; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; MelCAM; MUC 18; MUC18; MUC18; S endo 1; S endo 1 endothelial associated antigen; S-endo 1 endothelial-associated antigen
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Immunology; Signal Transduction; Stem Cells
Purification
Antigen affinity purification
Concentration
1.14 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

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