PSMA6 Polyclonal Antibody

• Background :

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

• Abbreviation :

  PSMA6

• UniProt :

  P60900

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Fusion protein of human PSMA6

• Target :

  27 kDa prosomal protein; IOTA; Macropain iota chain; Macropain subunit iota; MGC22756; MGC2333; MGC23846; Multicatalytic endopeptidase complex iota chain; p27K; PROS 27; PROS-27; PROS27; Prosomal P27K protein; Proteasome (prosome macropain) subunit alpha type 6; Proteasome iota chain; Proteasome subunit alpha type 6; Proteasome subunit alpha type-6; Proteasome subunit iota; PSA6; PSMA 6; PSMA6

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Cell Biology

• Purification :

  Antigen affinity purification

• Concentration :

  1.14 mg/mL

• Dilution :

  WB 1:1000-1:5000; IHC 1:50-1:200

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  27 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG