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DNAJA4 Polyclonal Antibody

CAT: 0763-E-AB-53105-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-53105-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.
Abbreviation
DNAJA4
UniProt
Q8WW22
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human DNAJA4
Target
DnaJ (Hsp40) homolog subfamily A member 4; DnaJ (Hsp40) homolog; subfamily A; member4; DNAJ A4; DnaJ heat shock protein family (Hsp40) member A4; DnaJ homolog subfamily A member 4; DNAJA 4; DNAJA4; DNJA4; MST104; MSTP104; PRO1472
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal transduction
Purification
Antigen affinity purification
Concentration
0.84 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

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