EIF4A3 Polyclonal Antibody

CAT: 0763-E-AB-52632-02Size: 60 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-52632-02Size:60 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Abbreviation

EIF4A3

UniProt

P38919

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Fusion protein of human EIF4A3

Target

ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-3; DDX48; DEAD box protein 48; eIF-4A-III; eIF4A-III; EIF4A3; eIF4AIII; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-like NUK-34; Eukaryotic translation initiation factor 4A isoform 3; hNMP 265; IF4A3; NMP 265; NMP265; Nuclear matrix protein 265; NUK34

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Antigen affinity purification

Concentration

1.2 mg/mL

Dilution

IHC 1:40-1:200

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P38919

Eukaryotic initiation factor 4A-III

IF4A3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P38919
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF4A3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-4A-III, eIF4A-III
EC number: 3.6.4.13
Processing: —
Secondary accessions: Q15033, Q6IBQ2, Q96A18

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleusSpliceosome

Disease

Disease variant

Molecular function

HelicaseHydrolaseRNA-binding

Biological process

mRNA processingmRNA splicingmRNA transportNonsense-mediated mRNA decayrRNA processingTranslation regulationTransport

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Catalog	Name
RD252632A-01	EIF4A3 Polyclonal Antibody
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