CD99 Polyclonal Antibody

• Background:

  CD99, also known as MIC2, is a heavily O-glycosylated transmembrane protein involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 is broadly distributed on many cell types, with particularly strong expression on human cortical thymocytes, Ewing’s sarcoma cells and peripheral primitive neuroectodermal tumors . In normal cells, CD99 has been functionally implicated in cell adhesion, migration, apoptosis, differentiation, activation, and proliferation of lymphocytes and monocyte extravasation and transport of several transmembrane proteins . CD99 displays two surface isoforms generated by alternative splicing: a long 32 kDa and a short 28 kDa form .

• Abbreviation:

  CD99

• UniProt:

  P14209

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human CD99

• Target:

  12E7; Antigen identified by monoclonal 12E7; Y homolog; Antigen identified by monoclonal antibodies 12E7; F21 and O13; CD99; CD99 antigen; CD99 molecule; CD99; Cell surface antigen 12E7; Cell surface antigen HBA 71; Cell surface antigen O13; E2 antigen; HBA71; MIC 2X; MIC 2Y; MIC2 (monoclonal 12E7) ; MIC2; MIC2X; MIC2Y; MSK5X; Protein MIC2; Surface antigen MIC2; T cell surface glycoprotein E2; T-cell surface glycoprotein E2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Immunology; Signal Transduction

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:40-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG