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LRRC19 Polyclonal Antibody

CAT: 0763-E-AB-52280-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52280-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Abbreviation
LRRC19
UniProt
Q9H756
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human LRRC19
Target
FLJ21302; Leucine rich repeat containing 19; leucine rich repeat containing protein 19; Leucine-rich repeat-containing protein 19; LRC19; LRRC 19; LRRC19
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Signal transduction
Purification
Antigen affinity purification
Concentration
1.1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:25-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

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