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SERPINB4 Polyclonal Antibody

CAT: 0763-E-AB-52213-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52213-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. SERPINB4 (Serpin Family B Member 4) is a Protein Coding gene. Diseases associated with SERPINB4 include Squamous Cell Carcinoma and Chromosome 18Q Deletion Syndrome. Among its related pathways are Amoebiasis. GO annotations related to this gene include enzyme binding and protease binding. An important paralog of this gene is SERPINB3.
Abbreviation
SERPINB4
UniProt
P48594
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human SERPINB4
Target
Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor (leucine serpin) ; SCCA 2; SCCA-2; SCCA1; SCCA2; SCCA2/SCCA1 fusion protein; Serine (or cysteine) proteinase inhibitor; clade B (ovalbumin) ; member 4; Serpin B4; Serpin peptidase inhibitor; clade B (ovalbumin) ; member 4; SERPINB 4; SERPINB4; SPB4; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cell Biology; Immunology
Purification
Antigen affinity purification
Concentration
0.72 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG