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KCNJ2 Polyclonal Antibody

CAT: 0763-E-AB-52110-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52110-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
Abbreviation
KCNJ2
UniProt
P63252
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human KCNJ2
Target
Cardiac inward rectifier potassium channel; HHBIRK 1; HHBIRK1; HHIRK 1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; Inward rectifier K (+) channel Kir2.1; Inward rectifier potassium channel 2; inwardly rectifying subfamily J member 2; IRK 1; IRK-1; IRK1; IRK2; KCNJ2; KIR2.1; LQT 7; LQT7; Potassium channel; Potassium channel inwardly rectifying subfamily J member 2; Potassium inwardly rectifying channel J2; Potassium inwardly rectifying channel subfamily J member 2; SQT 3; SQT3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience
Purification
Antigen affinity purification
Concentration
0.96 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P63252

Inward rectifier potassium channel 2

KCNJ2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P63252
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNJ2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
O15110, P48049
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

Atrial fibrillationDisease variantLong QT syndromeShort QT syndrome

Cellular component

Cell membraneMembrane

PTM

Disulfide bondS-nitrosylation

Molecular function

Ion channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Ligand

Potassium

Domain

TransmembraneTransmembrane helix

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