RegisterLogin

TNF Polyclonal Antibody

CAT: 0763-E-AB-52065-01Size: 20 µLDry Ice: NoHazardous: No
E-AB-52065-0120 µL
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
TNF, as also known as TNF-alpha, or cachectin, is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is expressed as a 26 kDa membrane bound protein and is then cleaved by TNF-alpha converting enzyme (TACE) to release the soluble 17 kDa monomer, which forms homotrimers in circulation. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Abbreviation
TNF
UniProt
P01375
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide of human TNF
Target
APC1; APC1 protein; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; Tnf; TNF superfamily; member 2; TNF; macrophage derived; TNF; monocyte derived; TNF-a; TNF-alpha; TNFA; TNFA; TNFSF2; Tumor necrosis factor alpha; Tumor necrosis factor; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor; Membrane Form; Tumor necrosis factor; soluble form
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Immunology; Signal Transduction
Purification
Antigen affinity purification
Concentration
1.14 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Related Products

CatalogName
E-AB-14410-01TNF beta Polyclonal Antibody
E-AB-33121-01TNF alpha Polyclonal Antibody
AN005930L-01TNF RI/TNFRSF1A Polyclonal Antibody
AN000820P-01TNF RI/TNFRSF1A Polyclonal Antibody (Capture/Detector)
AN300877L-01Recombinant TNF α Monoclonal Antibody
E-AB-22159-01TNF alpha Monoclonal Antibody
E-AB-22116-01TNF alpha Monoclonal Antibody
E-KAB-0094Mouse TNF-α Antibody Pair Set
E-KAB-0113Rat TNF-α Antibody Pair Set
E-KAB-0712Human TNF-β Antibody Pair Set

Alternative Products

CatalogName
APR00460GPolyclonal Spt16 polyclonal antibody
APR00449GPolyclonal Hira polyclonal antibody
APR00373GPolyclonal EzH2 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR12525GPolyclonal MeCP2 polyclonal antibody
APR14018GPolyclonal YY1 polyclonal antibody
AMR09486GPolyclonal PPARG polyclonal antibody
APR11188GPolyclonal Rtf1 polyclonal antibody

Popular Products