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MMP-7 Polyclonal Antibody

CAT: 0763-E-AB-40656-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-40656-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Matrix metalloproteinases (MMPs) are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-7 (matrilysin) is expressed in epithelial cells of normal and diseased tissues, and is capable of digesting a large series of proteins of the extracellular matrix including collagen IV and X, gelatin, casein, laminin, aggrecan, entactin, elastin and versican. MMP-7 is implicated in the activation of other proteinases such as plasminogen, MMP-1, MMP-2, and MMP-9.
Abbreviation
MMP-7
UniProt
P50280
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Rat MMP-7 protein expressed by E.coli
Target
MMP7 MPSL1 PUMP1; Matrilysin; Matrin; Matrix metalloproteinase-7; MMP-7; Pump-1 protease; Uterine metalloproteinase
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Signal transduction; Cell Biology; Neuroscience
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa
Observed Molecular Weight
30kDa
Isotype
IgG

UniProtKB · P50280

Matrilysin

MMP7_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P50280
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Mmp7
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
3.4.24.23
Processing
Precursor
Secondary accessions
—
Protein keywords

Ligand

CalciumMetal-bindingZinc

Biological process

Collagen degradation

Cellular component

Extracellular matrixSecreted

Molecular function

HydrolaseMetalloproteaseProtease

Technical term

Reference proteome

Domain

Signal

PTM

Zymogen
Product Datasheet
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