PAI1 Polyclonal Antibody

CAT: 0763-E-AB-40651-01Size: 25 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-40651-01Size:25 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU) . As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.
Abbreviation
PAI1
UniProt
P20961
Host
Rabbit
Reactivity
Rat
Immunogen
Recombinant Rat PAI1 protein expressed by Mammalian
Target
Plasminogen activator inhibitor 1; PAI-1; Endothelial plasminogen activator inhibitor; Serpin E1; SERPINE1; PLANH1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
47 kDa
Isotype
IgG
Product Datasheet
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