Serpin A1 Polyclonal Antibody

CAT: 0763-E-AB-40634-01Size: 25 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-40634-01Size:25 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Serpin A1 is the archetypal member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in the liver and secreted into the bloodstream with the major function to protect tissues against neutrophil elastase.A severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatitis, cirrhosis, and hepatocellular carcinoma.

Abbreviation

Serpin A1

UniProt

P17475

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Rat Serpin A1 protein expressed by E.coli

Target

Alpha 1 Antitrypsin; Serpina1; Alpha-1-antiproteinase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:100-1:200; IHC 1:2000-1:4000

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

46kDa

Observed Molecular Weight

60kDa

Isotype

IgG

UniProtKB · P17475

Alpha-1-antiproteinase

A1AT_RAT · Rattus norvegicus

View on UniProt ↗

Primary accession: P17475
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Serpina1
Protein existence: 1: Evidence at protein level
Organism: Rattus norvegicus (Rat)
Taxonomy ID: 10116
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q6AYZ5

Protein keywords

Biological process

Acute phase

Technical term

Direct protein sequencingReference proteome

PTM

GlycoproteinPhosphoprotein

Molecular function

Protease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

Product Datasheet

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