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S100A4 Polyclonal Antibody

CAT: 0763-E-AB-40458-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-40458-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Abbreviation
S100A4
UniProt
P26447
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human Protein S100-A4 protein
Target
18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; S100 calcium binding protein A4; S100a4
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cardiovascular; Signal Transduction; Cancer
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:500-1000; IHC 1:100-1:400
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11kDa
Observed Molecular Weight
11kDa
Isotype
IgG
Product Datasheet
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