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Pep63

CAT: 0804-HY-P10630Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10630Size:1 Each
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Description
Pep63 is a neuroprotective peptide (VFQVRARTVA) . Pep63 has a neuroprotective effect on synaptic plasticity and memory. Pep63 can competitively bind with Aβ1-42 oligomers, and can block Aβ fiber formation. Pep63 can be used for Alzheimer’s disease (AD) research[1].
CAS Number
1781242-18-9
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pep63.html
Smiles
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Molecular Formula
C51H87N17O13
Molecular Weight
1146.34
References & Citations
[1]Yang X, et al. Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer's disease models. Cell Death Discov. 2021 Sep 21;7 (1) :256.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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