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MAP2K6 Polyclonal Antibody

CAT: 0763-E-AB-40167-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-40167-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Abbreviation
MAP2K6
UniProt
P70236
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 6 protein
Target
MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; SAPKK-3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Immunology; Signal transduction
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:50-1:100
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P70236

Dual specificity mitogen-activated protein kinase kinase 6

MP2K6_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P70236
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Map2k6
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
MAP kinase kinase 6, MAPKK 6
EC number
2.7.12.2
Processing
—
Secondary accessions
—
Protein keywords

Biological process

ApoptosisStress responseTranscriptionTranscription regulation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

PTM

PhosphoproteinUbl conjugation

Technical term

Reference proteome

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