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Laminin alpha5 Polyclonal Antibody

CAT: 0763-E-AB-31903-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-31903-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
Abbreviation
Laminin α-5
UniProt
O15230
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Laminin α-5
Target
LAMA5; KIAA0533; KIAA1907; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
400kDa
Observed Molecular Weight
400kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S2352396419303275
Citation 02
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535067/
Citation 03
https://www.sciencedirect.com/science/article/pii/S0014483518305578
Isotype
IgG

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