C-Myc Polyclonal Antibody

• Background:

  Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

• Abbreviation:

  C-Myc

• UniProt:

  P01106

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human c-Myc around the non-phosphorylation site of Ser373.

• Target:

  AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; Class E basic helix-loop-helix protein 39; MRTL; Myc; Myc protein; Myc proto oncogene protein; Myc proto-oncogene protein; myc-related translation/localization regulatory factor; MYC; Myc2; MYCC; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; OTTHUMP00000158589; Proto-oncogene c-Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian)

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-p

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:300

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  49kDa

• Observed Molecular Weight:

  50-60kDa

• Citation 01:

  https://academic.oup.com/hmg/article-abstract/29/7/1132/5775612

• Citation 02:

  https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full

• Citation 03:

  https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.26718

• Isotype:

  IgG