CD284 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  CD284

• UniProt:

  O00206

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from the Internal region of human CD284.

• Target:

  ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-p; IF

• Field of Research:

  Cancer; Cardiovascular; Immunology; Microbiology

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:300; IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  96kDa

• Observed Molecular Weight:

  95kDa

• Isotype:

  IgG