ABCG2 Polyclonal Antibody

CAT: 0763-E-AB-30393-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-30393-01Size:20 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Abbreviation
ABCG2
UniProt
Q9UNQ0
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human ABCG2.
Target
ABC transporter; ABC15; ABCG 2; ABCG2; ABCG2; ABCP; ATP binding cassette sub family G (WHITE) member 2; ATP binding cassette transporter G2; ATP-binding cassette sub-family G member 2; BCRP; BCRP1; BMDP; Breast cancer resistance protein; CD338; CDw338; CDw338 antigen; EST157481; GOUT1; MGC102821; Mitoxantrone resistance associated protein; Mitoxantrone resistance-associated protein; MRX; Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2; MXR; MXR1; Placenta specific ATP binding cassette transporter; Placenta specific MDR protein; Placenta-specific ATP-binding cassette transporter; UAQTL1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p
Field of Research
Cancer; Metabolism; Signal Transduction; Stem Cells; Tags and Cell Markers
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
72kDa
Observed Molecular Weight
72kDa
Citation 01
https://link.springer.com/article/10.1007/s10989-021-10212-0
Isotype
IgG

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