ABCG2 Polyclonal Antibody

• Background :

  Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

• Abbreviation :

  ABCG2

• UniProt :

  Q9UNQ0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Synthesized peptide derived from the Internal region of human ABCG2.

• Target :

  ABC transporter; ABC15; ABCG 2; ABCG2; ABCG2; ABCP; ATP binding cassette sub family G (WHITE) member 2; ATP binding cassette transporter G2; ATP-binding cassette sub-family G member 2; BCRP; BCRP1; BMDP; Breast cancer resistance protein; CD338; CDw338; CDw338 antigen; EST157481; GOUT1; MGC102821; Mitoxantrone resistance associated protein; Mitoxantrone resistance-associated protein; MRX; Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2; MXR; MXR1; Placenta specific ATP binding cassette transporter; Placenta specific MDR protein; Placenta-specific ATP-binding cassette transporter; UAQTL1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC-p

• Field of Research :

  Cancer; Metabolism; Signal Transduction; Stem Cells; Tags and Cell Markers

• Purification :

  Affinity purification

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:100-1:300

• Buffer :

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  72kDa

• Observed Molecular Weight :

  72kDa

• Citation 01 :

  https://link.springer.com/article/10.1007/s10989-021-10212-0

• Isotype :

  IgG