Phospho-EEF2K (Ser366) Polyclonal Antibody

• Background:

  This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

• Abbreviation:

  EEF2K (phospho Ser366)

• UniProt:

  O00418

• Host:

  Rabbit

• Reactivity:

  Human; Rat

• Immunogen:

  Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

• Target:

  C86191; Calcium/calmodulin dependent eukaryotic elongation factor 2; Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; Calmodulin dependent protein kinase III; cb365; EC 2.7.11.20; eEF 2 kinase; eEF 2K; eEF-2 kinase; eEF-2K; Eef2k; EEF2K protein; EF2K; Elongation factor 2 kinase; Eukaryotic elongation factor 2 kinase; fa04b08; HSU93850; kinase eEF2K; MGC45041; SMEF2K; wu:fa04b08; zgc:100973

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-p

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:100-1:300

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  82kDa

• Observed Molecular Weight:

  105kDa

• Isotype:

  IgG