CITED4 Polyclonal Antibody

• Background:

  The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.

• Abbreviation:

  CITED4

• UniProt:

  Q96RK1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human CITED4

• Target:

  AU019445; AW742964; Cbp/p300 interacting transactivator 4; cbp/p300 interacting transactivator; with glu/asp rich carboxy terminal domain; 4; Cbp/p300-interacting transactivator 4; CITE4; Cited4; MRG 2; MRG-2; Mrg2; MSG1 related protein 2; MSG1-related protein 2; Transcriptional co-activator 4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Metabolism

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:30-1:150

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG