CDKL4 Polyclonal Antibody

• Background:

  Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

• Abbreviation:

  CDKL4

• UniProt:

  Q5MAI5

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human CDKL4

• Target:

  CDKL4; CDKL4; Cyclin dependent kinase like 4; Cyclin-dependent kinase-like 4; EC 2.7.11.22; OTTHUMP00000164944

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cell Biology; Signal Transduction

• Purification:

  Antigen affinity purification

• Concentration:

  0.8 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG