CDKL4 Polyclonal Antibody

• Background :

  Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

• Abbreviation :

  CDKL4

• UniProt :

  Q5MAI5

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthetic peptide of human CDKL4

• Target :

  CDKL4; CDKL4; Cyclin dependent kinase like 4; Cyclin-dependent kinase-like 4; EC 2.7.11.22; OTTHUMP00000164944

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cell Biology; Signal Transduction

• Purification :

  Antigen affinity purification

• Concentration :

  0.8 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  43 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG