IRF5 Polyclonal Antibody

• Background:

  IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10) .

• Abbreviation:

  IRF5

• UniProt:

  Q13568

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human IRF5

• Target:

  Interferon regulatory factor 5; Interferon regulatory factor 5 bone marrow variant; IRF 5; IRF-5; Irf5; IRF5; SLEB10

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Immunology

• Purification:

  Antigen affinity purification

• Concentration:

  0.7 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:25-1:100

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  56 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG