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METTL1 Polyclonal Antibody

CAT: 0763-E-AB-18960-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18960-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.
Abbreviation
METTL1
UniProt
Q9UBP6
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human METTL1
Target
C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like 1; Methyltransferase like protein 1; Methyltransferase-like protein 1; Mettl1; TRM8; TRMB_HUMAN; TRMT8; tRNA (guanine N (7) ) methyltransferase; tRNA (guanine (46) -N (7) ) -methyltransferase; tRNA (guanine-N (7) -) -methyltransferase; tRNA (m7G46) methyltransferase; tRNA (m7G46) -methyltransferase; YDL201w
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9UBP6

tRNA (guanine-N(7)-)-methyltransferase

TRMB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBP6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METTL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.33
Processing
—
Secondary accessions
B2RBX1, H7BXF2, Q14105, Q53FS9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Molecular function

MethyltransferaseRNA-bindingTransferasetRNA-binding

Cellular component

Nucleus

Ligand

S-adenosyl-L-methionine

Biological process

tRNA processing

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