c-Kit-IN-1

c-Kit-IN-1

• CAS Number: 1225278-16-9
• UNSPSC Description: c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of <200 nM.
• Target Antigen: c-Kit; c-Met/HGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-Kit-IN-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1(CC1)C(NC2=CC=CC=C2)=O)NC3=CC(F)=C(OC4=CC=NC(C5=CN(C)N=C5)=C4)C=C3F
• Molecular Weight: 489.47
• References & Citations: [1]Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
• Shipping Conditions: Room Temperature
• Clinical Information: Launched