RBM15 Polyclonal Antibody

CAT: 0763-E-AB-18870-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0763-E-AB-18870-01Size:20 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t (1,22) (p13; q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.

Abbreviation

RBM15

UniProt

Q96T37

Host

Rabbit

Reactivity

Human

Immunogen

Fusion protein of human RBM15

Target

One twenty two protein; One-twenty two protein 1; OTT; OTT1; Putative RNA-binding protein 15; RBM15; RBM15; RNA binding motif protein 15; RNA-binding motif protein 15

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling; Stem Cells

Purification

Antigen affinity purification

Concentration

1.2 mg/mL

Dilution

IHC 1:50-1:300

Buffer

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · Q96T37

RNA-binding protein 15

RBM15_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q96T37
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: RBM15
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A1A693, Q3ZB86, Q4V760, Q5D058, Q5T613, Q86VW9, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Biological process

Host-virus interaction

Cellular component

MembraneNucleus

Disease

Proto-oncogene

Domain

Repeat

Molecular function

RNA-binding

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Alternative Products

Catalog	Name
MBS129290-01	RBM15 Polyclonal Antibody
NBP1-31364	Rabbit Polyclonal RBM15 Antibody
TA308434	RBM15 Rabbit Polyclonal Antibody
MBS9441799-01	RBM15 Polyclonal Conjugated Antibody