CD86 Polyclonal Antibody

• Background:

  This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

• Abbreviation:

  CD86

• UniProt:

  P42081

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Fusion protein of human CD86

• Target:

  Activation B7-2 antigen 3; Activation B7-2 antigen; B-lymphocyte activation antigen B7-2 2; B-lymphocyte activation antigen B7-2; B7 2; B7; B7-2; B7.2; B70; B72 antigen; BU63; CD28 antigen ligand 2 2; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen; CD86 molecule; CD86; CLS1; CTLA-4 counter-receptor B7.2 2;3; CTLA-4 counter-receptor B7.2; Early T-cell costimulatory molecule 1; ETC-1; FUN 1; FUN-1; LAB72; Ly-58; Ly58; MB7; MB7-2; Membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Immunology; Microbiology; Stem Cells

• Purification:

  Antigen affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:25-1:100

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  38 kDa

• Observed Molecular Weight:

  Refer to figures

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S1567576919322672

• Citation 02:

  https://peerj.com/articles/8294/

• Isotype:

  IgG