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CD1B Polyclonal Antibody

CAT: 0763-E-AB-17775-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-17775-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Immune System Organ Benign Neoplasm. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1C.This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Abbreviation
CD1B
UniProt
P29016
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human CD1B
Target
A1 domain; CD1; CD1A; CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Differentiation antigen CD1 alpha 3; hTa1 thymocyte antigen; Ly38; Ly38; T cell surface glycoprotein CD1a; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b; T6/Leu6; Thymocite antigen CD1B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology
Purification
Antigen affinity purification
Concentration
1.4 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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