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TNFRSF13C Polyclonal Antibody

CAT: 0763-E-AB-16646-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16646-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE) . Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Abbreviation
TNFRSF13C
UniProt
Q96RJ3
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human TNFRSF13C
Target
B cell activating factor receptor; B-cell-activating factor receptor; BAFF R; BAFF receptor; BAFF-R; BAFFR; BLyS receptor 3; BlySR3; BR 3; BR3; BROMIX; CD 268; CD268; CD268 antigen; CVID4; MGC138235; OTTHUMP00000028746; Prolixin; TNFRSF 13C; Tnfrsf13c; TR13C; Tumor necrosis factor receptor subunit member 13C; Tumor necrosis factor receptor superfamily member 13C
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Signal transduction
Purification
Affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96RJ3

Tumor necrosis factor receptor superfamily member 13C

TR13C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96RJ3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFRSF13C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Disease

Disease variant

PTM

Disulfide bond

Cellular component

Membrane

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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