HMGCS2 Polyclonal Antibody

CAT: 0763-E-AB-16483-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-16483-01Size:20 µL
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Background
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
HMGCS2
UniProt
P54868
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human HMGCS2
Target
3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial) ;3 hydroxy 3 methylglutaryl Coenzyme A synthase 2;3 hydroxy 3 methylglutaryl coenzyme A synthase;3-hydroxy-3-methylglutaryl coenzyme A synthase; HMCS2; HMG CoA synthase; HMG-CoA synthase; HMGCS 2; HMGCS2; Hydroxymethylglutaryl CoA synthase; Hydroxymethylglutaryl CoA synthase mitochondrial; Hydroxymethylglutaryl-CoA synthase; mitochondrial
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Cardiovascular; Metabolism; Signal transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57kDa
Isotype
IgG

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