SNCA Polyclonal Antibody

• Background:

  Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

• Abbreviation:

  SNCA

• UniProt:

  P37840

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthetic peptide of human SNCA

• Target:

  Alpha synuclein; Alpha-synuclein; Alpha-synuclein; isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid; Non A4 component of amyloid precursor; Non-A beta component of AD amyloid; Non-A-beta component of alzheimers disease amyloid; precursor of; Non-A4 component of amyloid precursor; Non-A4 component of amyloid; precursor of; OTTHUMP00000218549; OTTHUMP00000218551; OTTHUMP00000218552; OTTHUMP00000218553; OTTHUMP00000218554; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease (autosomal dominant; Lewy body) 4; Parkinson disease familial 1; SNCA; Snca synuclein; alpha (non A4 component of amyloid precursor) ; SYN; Synuclein alpha; Synuclein alpha 140; Synuclein; alpha (non A4 component of amyloid precursor) ; SYUA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Neuroscience

• Purification:

  Affinity purification

• Concentration:

  0.4 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG