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SLC8A3 Polyclonal Antibody

CAT: 0763-E-AB-15997-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15997-02Size:60 µL
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Background
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.
Abbreviation
SLC8A3
UniProt
P57103
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human SLC8A3
Target
AW742262; MGC90626; Na+/Ca2+ exchange protein 3; Na+/Ca2+ exchanger 3; NAC3; NCX3; SCL8A3; Sodium calcium exchanger form 3; Sodium/calcium exchanger 3; Sodium/calcium exchanger SLC8A3; Solute carrier family 8 sodium calcium exchanger member 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Metabolism; Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P57103

Sodium/calcium exchanger 3

NAC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P57103
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC8A3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5K3P6, Q5K3P7, Q8IUE9, Q8IUF0, Q8NFI7, Q96QG1, Q96QG2
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AntiportCalcium transportIon transportSodium transportTransport

Ligand

CalciumMetal-bindingSodium

Molecular function

Calmodulin-binding

Cellular component

Cell junctionCell membraneCell projectionCytoplasmEndoplasmic reticulumMembraneMitochondrionMitochondrion outer membraneSynapse

PTM

Glycoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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